Choroideremia (CHM) is a rare X-linked chorioretinal dystrophy, affecting the photoreceptors, retinal pigment epithelium (RPE) and choroid, with no approved therapy.CHM is caused by mutations in the CHM gene, which encodes the ubiquitously expressed Rab escort protein 1 (REP1).REP1 is involved in prenylation, a post-translational modification of Ra
This article intends to develop a historical, theoretical and critical debate about mental health, as a social policy, resulting from the dialectical relationship between state and civil Work Saddles society.The adopted methodology is qualitative, consisting on a bibliographical and reflexive review, through which it aims to evaluate positions of v
Intensified chemoimmunotherapy regimens are often used in young patients with double hit and triple hit lymphoma (DHL/THL) despite no survival benefit compared to R-CHOP.Favorable retrospective reports on the application of CODOX-M/IVAC-R are subject to selection bias as only Play Tents young fit patients can tolerate this treatment.We conducted a
Primary hyperthyroidism is a rarely diagnosed endocrinopathy in equids and there have been no previous reports of structural and functional cardiac changes associated with hyperthyroidism in these species.This case report investigates a 20-year-old mule gelding Clothes Line that presented for a three-month history of thin body condition despite pol
Lumbricals are wormlike, intrinsic muscle of the hand.During routine dissection of a male cadaver of age approximately ranging between 50 and 55 years, the absence of third and fourth lumbricals on both the palm was observed.First and second lumbricals showed no anatomical variation.Other muscles of hypothenar eminence supplied Bathroom Safety by d